It appears in "The Inconveniencing." Mabel thought that the candy was banned in the United States; however, the Dusk 2 Dawn still carried it. After eating "eleventeen" packages of Smile Dip, Mabel began to hallucinate. Among her hallucinations were the two Flavor Pups (the Smile Dip mascots), one of whom offered her a candy paw, and an aqua colored dolphin with muscles, horn honks, and four arms that constantly hurled out endless rainbow trails. While riding it, she shouts,"Onwards Aoshima!" At the end of the episode, Mabel says Smile Dip is "evil" and she will never eat or do anything again because of it. In the episode "Boyz Crazy" Mabel begins dancing along to her favorite band and Dipper mentions Smile Dip.
- It is most likely an allusion to the candy "Fun Dip."
- The hallucinations that it caused resembles Lisa Frank artwork.